Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length159 amino acids

Chemical FormulaC776H1226N202O250S16

DescriptionStandard

        MNILMLTFIICGLLTQVTKGSFEPQKCWKNNIGHCRRRCLDTERCILLCRNKLSCCIYIIISHEYTQRSAFPMIHLEDITFDYSDVDSFTGSPVSMLNDLMTFDTTKFGETMTPETNTPETTTTVPPSETTTPETTMPPSETATSETMPPPSQTALTHN
    

Molecular Weight17898.28 Da

Isoelectric Point (pI)4.97

Net Charge (pH 7.0)-7.20

Net Charge (pH 7.4) -7.77

Charge Density (pH 7.0) -0.0453

GRAVY Index-0.29

Hydrophobic Moment 0.60

Boman Index0.03

Instability Index65.88

Aliphatic Index 65.60

Aromaticity 0.0692

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7194.14

LogP -81.11

H-bond Donors 255.0

H-bond Acceptors 263.0

Rotatable Bonds 573.0

Heavy Atoms 1244.0

Ring Count 29.0

Amide Bonds 169.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0029789 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9593

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence