Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitory peptide 1

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC21H37N5O6

DescriptionStandard

        QLVP
    

Molecular Weight455.55 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0600

GRAVY Index0.72

Hydrophobic Moment 0.52

Boman Index0.35

Instability Index55.65

Aliphatic Index 170.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 184.92

LogP -0.67

H-bond Donors 5.0

H-bond Acceptors 6.0

Rotatable Bonds 12.0

Heavy Atoms 32.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0137141 VERIFIED: YES

Provenance & Taxonomy

OrganismGanoderma lucidum [Fungus]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity127.9 μM

MethodIC50

RECORD: Rec_0390203 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity127.9

MethodIC50