Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2586H4020N642O744S17

DescriptionStandard

        MCTKMVQVLWGCFLLWNLYISSTQTTYPGIKARATQRALDYGVQAGVLMIEQMIKERNIPDLKGSESLEFLKVDYVNYNFSNIKINAFSFPNTSLAFVPGVGIKALTNHGTANISTNWDVKSPLFQDTGGADLFLSGIYFTGILILAQNDFGQPTLKLQDCYAQVSHAHVSFTGELSVLYNSFAEPMEKPILKNLNEMLCPIITGEVEALNANLSMLEVLTKIDNYTLLDYSLMSSPEITENYIDLNLKGVFYPLENLTDPPFSPLPFVLPERSDSMFYIGISEYFFKSASFAHFTAGAFNITLSTKEISSHLVRHSQGVGNVLSRIAEIYILSQPFMVRIMATEPPVISLLPGNFTLDIPASIVILTQSENSTAETIVSMDFVASTSVSLVILGQRLICSLSLNRFRLSLPESNRSNIEVLRFENILSFILHFGILPLANAKLQQGFPLPNPHKISFVNSDIEVLEHFLLISTDLKYETPLKQQPSFYGWEGLNLISGRWRGKSVP
    

Molecular Weight56552.54 Da

Isoelectric Point (pI)5.37

Net Charge (pH 7.0)-10.70

Net Charge (pH 7.4) -11.56

Charge Density (pH 7.0) -0.0211

GRAVY Index0.16

Hydrophobic Moment 0.67

Boman Index0.18

Instability Index42.72

Aliphatic Index 103.83

Aromaticity 0.1065

Extinction Coeff. Reduced 52830.00

Extinction Coeff. Oxidized 53080.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283499 VERIFIED: NO

Provenance & Taxonomy

OrganismMolossus molossus (Pallas` mastiff bat) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria