Peptide Database

Peptide NameCyclotide vibi-H (Plant defensin)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC142H235N35O42S6

DescriptionStandard

        GLLPCAESCVYIPCLTTVIGCSCKSKVCYKN
    

Molecular Weight3296.98 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0548

GRAVY Index0.67

Hydrophobic Moment 0.33

Boman Index0.21

Instability Index35.95

Aliphatic Index 94.19

Aromaticity 0.0645

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1218.80

LogP -12.22

H-bond Donors 48.0

H-bond Acceptors 50.0

Rotatable Bonds 104.0

Heavy Atoms 225.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423335 VERIFIED: NO

Provenance & Taxonomy

OrganismViola biflora [Animal]

FamilyCyclotide

Structure & Mods

Configbackbone-cyclized cyclotide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

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