Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length197 amino acids

Chemical FormulaC1009H1511N223O302S8

DescriptionStandard

        IDDLAEVDYSLSSLPAVFQPFIDLDLKGTVFPAGNYTGSPYEVAPFSVTDQSDSMLFLAFSEYFFQTSSFAYYTAGAFNMTIAEEVITHLFSLFYFFFQTCSYFNISTEIFGSIIPEVAKHSVTPYPVMLKLMAIEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNVAANSSISLNIFDQKLVGSLCLNR
    

Molecular Weight21853.62 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-16.06

Net Charge (pH 7.4) -16.43

Charge Density (pH 7.0) -0.0815

GRAVY Index0.43

Hydrophobic Moment 0.55

Boman Index0.28

Instability Index46.09

Aliphatic Index 94.52

Aromaticity 0.1472

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8282.82

LogP -95.91

H-bond Donors 282.0

H-bond Acceptors 296.0

Rotatable Bonds 695.0

Heavy Atoms 1542.0

Ring Count 41.0

Amide Bonds 211.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133657 VERIFIED: NO

Provenance & Taxonomy

OrganismNeopipo cinnamomea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria