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MYP_169244
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Basic Information
TP1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C85H134N24O21S2
Standard
Sequence
MRRKVELFTYMRFD
Physicochemical Analysis
1892.25 Da
9.98
1.51
1.28
0.1075
-0.64
0.45
-0.34
73.56
48.57
0.2143
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
768.40
-4.02
29.0
25.0
64.0
132.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0040447 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
RD cells
683
CC50
PaperPubMed PMID: 34314773 PMID34314773 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34314773/
RECORD: Rec_0145480 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Free
Bio-Activity Profile
Antiviral Replication inhibition
Enterovirus A71 (EV-A71) | RD cells
6.6 μM
IC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperStability and antiviral activity of SP40 peptide in human serum. | Zarif F, Anasir MI, Koh JX, Chew MF, Poh CL. | Virus Res. 2021 Oct 2;303:198456. | DOI:10.1016/j.virusres.2021.198456. | PMID:34314773 PMID34314773 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34314773/
RECORD: Rec_0229579 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 34314773 PMID34314773 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34314773/
RECORD: Rec_0398362 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 34314773 PMID34314773 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34314773/
RECORD: Rec_0419707 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
Enterovirus A71 (EV-A71):inhibition of viral replication into RD cells
6.6 μM
IC50
PaperPubMed PMID: 34314773 PMID34314773 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34314773/