Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC365H584N110O108S11

DescriptionStandard

        MEKKSLAGLCFLFLVLFVAQEVMVKTEARTCENLADTFRGPCFSSARCDDHCKNKEHLVSGRCRDDVRCWCTRNC
    

Molecular Weight8593.93 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)1.60

Net Charge (pH 7.4) 1.13

Charge Density (pH 7.0) 0.0213

GRAVY Index-0.20

Hydrophobic Moment 0.72

Boman Index-0.12

Instability Index27.04

Aliphatic Index 66.27

Aromaticity 0.0800

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3551.68

LogP -37.65

H-bond Donors 135.0

H-bond Acceptors 123.0

Rotatable Bonds 289.0

Heavy Atoms 594.0

Ring Count 10.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422521 VERIFIED: NO

Provenance & Taxonomy

OrganismCanavalia gladiata [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal