Peptide Database

Peptide NameChimeric CNP-G

Function Ontology

Natriuretic

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC162H279N51O45S3

DescriptionStandard

        VQQRKESKKPPAKLQPRCFGLKLDRIGSMSGLGC
    

Molecular Weight3757.46 Da

Isoelectric Point (pI)10.20

Net Charge (pH 7.0)5.71

Net Charge (pH 7.4) 5.46

Charge Density (pH 7.0) 0.1680

GRAVY Index-0.70

Hydrophobic Moment 0.58

Boman Index-0.23

Instability Index46.40

Aliphatic Index 68.82

Aromaticity 0.0294

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1577.61

LogP -17.25

H-bond Donors 56.0

H-bond Acceptors 54.0

Rotatable Bonds 131.0

Heavy Atoms 261.0

Ring Count 4.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0184360 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNatriuretic peptide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide18-34

Bio-Activity Profile

Function

Natriuretic

MethodCompetitive Radioimmunoassay

Half-LifeRat plasma (Intravenous), in vivo; 1065 s