Peptide Database

Peptide NameDermaseptin S4 (3-28)a

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC123H213N33O30S

DescriptionStandard

        WMTLLKKVLKAAAKAALNAVLVGANA
    

Molecular Weight2666.28 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1445

GRAVY Index0.90

Hydrophobic Moment 0.71

Boman Index0.30

Instability Index1.29

Aliphatic Index 139.23

Aromaticity 0.0385

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1017.10

LogP -6.37

H-bond Donors 35.0

H-bond Acceptors 35.0

Rotatable Bonds 90.0

Heavy Atoms 187.0

Ring Count 2.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351507 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDermaseptin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

Targethuman erythrocytes

RECORD: Rec_0419135 VERIFIED: NO