MYP_169098
Dermaseptin S4 (3-28)a
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
▸
Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Standard
26 amino acids
C123H213N33O30S
Standard
WMTLLKKVLKAAAKAALNAVLVGANA
2666.28 Da
10.48
3.76
3.55
0.1445
0.90
0.71
0.30
1.29
139.23
0.0385
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1017.10
-6.37
35.0
35.0
90.0
187.0
2.0
27.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0176918
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
RECORD: Rec_0196268
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
E. coli Urine DS, S2 = E. coli Urine MDR, S3 = K. pneumoniae Urine DS, S4 = C. striatum Wound exudate MDR, S5 = C. striatum Wound exudate MDR, S6 = C. striatum Wound exudate MDR, S7 = C. striatum Wound exudate MDR (DS = drug sensitive, MDR = multi drug resistant), C-terminal: CONH2
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
S5
225.33 μg/mL
MIC
RECORD: Rec_0216565
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
E. coli Urine DS, S2 = E. coli Urine MDR, S3 = K. pneumoniae Urine DS, S4 = C. striatum Wound exudate MDR, S5 = C. striatum Wound exudate MDR, S6 = C. striatum Wound exudate MDR, S7 = C. striatum Wound exudate MDR (DS = drug sensitive, MDR = multi drug resistant), C-terminal: CONH2
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
S7
267.54 μg/mL
MIC
RECORD: Rec_0262163
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
E. coli Urine DS, S2 = E. coli Urine MDR, S3 = K. pneumoniae Urine DS, S4 = C. striatum Wound exudate MDR, S5 = C. striatum Wound exudate MDR, S6 = C. striatum Wound exudate MDR, S7 = C. striatum Wound exudate MDR (DS = drug sensitive, MDR = multi drug resistant), C-terminal: CONH2
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
S2
334.33 μg/mL
MIC
RECORD: Rec_0270518
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
E. coli Urine DS, S2 = E. coli Urine MDR, S3 = K. pneumoniae Urine DS, S4 = C. striatum Wound exudate MDR, S5 = C. striatum Wound exudate MDR, S6 = C. striatum Wound exudate MDR, S7 = C. striatum Wound exudate MDR (DS = drug sensitive, MDR = multi drug resistant), C-terminal: CONH2
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
S4
235.84 μg/mL
MIC
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