Peptide Database

Peptide NameSLAY-screened peptide P3404

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC42H61N13O15S

DescriptionStandard

        WCSADPRAD
    

Molecular Weight1020.08 Da

Isoelectric Point (pI)4.54

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.46

Charge Density (pH 7.0) -0.1383

GRAVY Index-0.97

Hydrophobic Moment 0.24

Boman Index-0.23

Instability Index-18.36

Aliphatic Index 22.22

Aromaticity 0.1111

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 459.85

LogP -5.32

H-bond Donors 17.0

H-bond Acceptors 15.0

Rotatable Bonds 28.0

Heavy Atoms 71.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162000 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/