Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC340H534N80O91S11

DescriptionStandard

        MKTLLIMLVFLFLWDPVLAGINSLPSEMHKKCYKNGICRLECYESEMLVAYCMFQLECCVTGNPAP
    

Molecular Weight7551.07 Da

Isoelectric Point (pI)5.62

Net Charge (pH 7.0)-1.46

Net Charge (pH 7.4) -1.84

Charge Density (pH 7.0) -0.0222

GRAVY Index0.49

Hydrophobic Moment 0.53

Boman Index0.24

Instability Index55.87

Aliphatic Index 98.94

Aromaticity 0.1061

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2688.11

LogP -15.07

H-bond Donors 96.0

H-bond Acceptors 102.0

Rotatable Bonds 245.0

Heavy Atoms 522.0

Ring Count 13.0

Amide Bonds 69.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0338048 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinopithecus roxellana [Animal]

FamilyDefensin

Tax ID61622

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0427084 VERIFIED: NO