Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC435H685N123O117S10

DescriptionStandard

        MKFLILFLAIFLIKEPMIPGKSHPLRCMGNKGTCRNSCRKNEHPYLYCRNYQSCCLQSYMRINITGIEAKDDWTQDNRWPKLS
    

Molecular Weight9830.50 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)6.62

Net Charge (pH 7.4) 6.19

Charge Density (pH 7.0) 0.0797

GRAVY Index-0.47

Hydrophobic Moment 0.43

Boman Index-0.09

Instability Index61.72

Aliphatic Index 72.89

Aromaticity 0.1084

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3902.42

LogP -33.91

H-bond Donors 141.0

H-bond Acceptors 136.0

Rotatable Bonds 326.0

Heavy Atoms 685.0

Ring Count 18.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348724 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9365

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic