Peptide Database

Peptide NameAlpha-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC433H712N126O140S9

DescriptionStandard

        MRTLALLAAILLMALQAQADPLRQADDEAPAQDEPETGDQDMAVSFAGDERSVQEASGLKKTVICYCRRARCLSSELLSGICTISGVRYPFCCR
    

Molecular Weight10211.63 Da

Isoelectric Point (pI)4.79

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -3.86

Charge Density (pH 7.0) -0.0376

GRAVY Index-0.04

Hydrophobic Moment 0.53

Boman Index-0.02

Instability Index53.90

Aliphatic Index 88.40

Aromaticity 0.0426

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4288.13

LogP -47.60

H-bond Donors 155.0

H-bond Acceptors 146.0

Rotatable Bonds 341.0

Heavy Atoms 708.0

Ring Count 8.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018382 VERIFIED: NO

Provenance & Taxonomy

OrganismMammuthus primigenius [Animal]

FamilyDefensin

Tax ID37349

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

RECORD: Rec_0158729 VERIFIED: NO