Peptide Database

Peptide NameHNHc domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length637 amino acids

Chemical FormulaC3087H4944N866O928S11

DescriptionStandard

        MGGVLTPAGQMAPIFSVPGVGSLALTDTIGASLLAELNSAINTLNTVATTTADVALNAVSRGFVLASIFYSPAVGTGSDIVPGRTRENFLSLSVPAKAMGLPHRDALQQAAKTSGVISLPVRGKLAVTERQVDVRVVKTQNIQSVRVVEASHDENTGLYTHSLPDNDIGELNIVTTPIKESVIQGQPPLVTPLPTVPIKMHHDGHSSSASKPLPIPVSKATAFHDVIVVYPEAAKMEPVYVMFEPKAHSIAEAARQHHPEPLTEEITETKGLVKVKSRTASKTGEGMKGRWLSAVDGAIYEWNSEIGKLEVVQHPSKAAEQSLKEAGEHHYPTPLTESLTDYRGLLESRVKTPVADGKGKKFRWTDATGETLYEWNPLTGKMETYKAGRWETEINRSGESVRIWVVESVIDPATGLYGITLPDEQGKQGRTVLISPIKAPGANGLGHLLHPEGRQIVILNTGNGAPVKTPLVTVYPNPVQPNIDSQIAVPPLETNYKPLYVMFNNPRHLPGVVTGKGQEVTGNWLSKAGEELGAPIPSQIADNLRGKKFNNFDEFRRKFWEEVSKDTELSKQFIKSNRDRMLVGKAPKSRKKDTIGKRSSFELHHEKQISKGGEVYNMDNLRVTTPKKHIDIHRGKQ
    

Molecular Weight69390.24 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)8.33

Net Charge (pH 7.4) 6.93

Charge Density (pH 7.0) 0.0131

GRAVY Index-0.38

Hydrophobic Moment 0.66

Boman Index0.00

Instability Index36.67

Aliphatic Index 84.76

Aromaticity 0.0565

Extinction Coeff. Reduced 64860.00

Extinction Coeff. Oxidized 64860.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032180 VERIFIED: NO

Provenance & Taxonomy

OrganismArsenophonus sp. ENCA [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence