Peptide Database

Peptide NameGremlin-1

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length160 amino acids

Chemical FormulaC781H1266N244O239S12

DescriptionStandard

        KKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD
    

Molecular Weight18282.68 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)13.04

Net Charge (pH 7.4) 12.45

Charge Density (pH 7.0) 0.0815

GRAVY Index-1.08

Hydrophobic Moment 0.57

Boman Index-0.28

Instability Index60.74

Aliphatic Index 48.12

Aromaticity 0.0563

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7920.85

LogP -96.74

H-bond Donors 280.0

H-bond Acceptors 268.0

Rotatable Bonds 622.0

Heavy Atoms 1276.0

Ring Count 26.0

Amide Bonds 179.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378793 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDAN family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide70-120; 84-134; 94-152; 98-154

Bio-Activity Profile

Function

Cytokine Growth factor DAN family Growth factor signaling Angiogenic