MYP_168992
Brevinin-1ITa
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antibiotic activity
Antimicrobial
▸
Antifungal
Immunology
▸
Innate immune defense
▸
Host defense peptide
▸
Defense peptide
Toxicity / Safety
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Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytolysis / cell lysis
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Cytolytic activity
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
Standard
20 amino acids
C105H183N23O22S3
Standard
IVPFLLGMVPKLVCLITKKC
2215.91 Da
9.39
2.74
2.50
0.1369
1.52
0.54
0.44
39.53
160.50
0.0500
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
696.93
0.12
25.0
28.0
72.0
153.0
3.0
19.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0115320
VERIFIED: YES
Provenance & Taxonomy
skin secretions of the Italian stream frog Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
RECORD: Rec_0193275
VERIFIED: NO
Provenance & Taxonomy
Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus epidermidis, Escherichia coli
RECORD: Rec_0199548
VERIFIED: YES
Provenance & Taxonomy
Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-20
Bio-Activity Profile
Antimicrobial
Antifungal
Staphylococcus epidermidis, Escherichia coli
RECORD: Rec_0224630
VERIFIED: YES
Provenance & Taxonomy
Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Staphylococcus epidermidis
4 μM
MIC
RECORD: Rec_0263784
VERIFIED: YES
Provenance & Taxonomy
skin secretions of the Italian stream frog Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
HT-29
18 μM
LC50
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