‹ ›
MYP_168992
← PREVIOUS NEXT → BACK
Basic Information
Brevinin-1ITa
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C105H183N23O22S3
Standard
Sequence
IVPFLLGMVPKLVCLITKKC
Physicochemical Analysis
2215.91 Da
9.39
2.74
2.50
0.1369
1.52
0.54
0.44
39.53
160.50
0.0500
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
696.93
0.12
25.0
28.0
72.0
153.0
3.0
19.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0015760 VERIFIED: YES
Provenance & Taxonomy
Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Cytotoxic Hemolytic
Escherichia coli (Gram-negative)
PMID28699258 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28699258/
RECORD: Rec_0045469 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the Italian stream frog Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
18 μM
LC50
PaperPubMed PMID: 28699258 PMID28699258 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28699258/
RECORD: Rec_0064896 VERIFIED: YES
Provenance & Taxonomy
Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
64 μM
MIC
PMID28699258 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28699258/
RECORD: Rec_0070686 VERIFIED: YES
Provenance & Taxonomy
Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida parapsilosis
16 μM
MIC
PMID28699258 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28699258/
RECORD: Rec_0094892 VERIFIED: YES
Provenance & Taxonomy
Rana italica [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Cytotoxic Hemolytic
C. parapsilosis
PMID28699258 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28699258/
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3