Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length181 amino acids

Chemical FormulaC887H1397N273O258S11

DescriptionStandard

        MPRHIKRYAVATIVALGVTLAPGALRTSEEAQVKIATWEDCRARPYYDTAGILTTGCGSTGNVKNRLYSENEVAERWVNDMQRAENCINKNFHGAAMPQSVFEAMTDAAYNLGCTSLMWFKDRRGQRHRTTIWKHAQAHRWIQACARLTDFVNSGGKRIPGLVNRRTDFKAWCLKDTGATS
    

Molecular Weight20365.97 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)9.89

Net Charge (pH 7.4) 9.30

Charge Density (pH 7.0) 0.0547

GRAVY Index-0.48

Hydrophobic Moment 0.78

Boman Index-0.09

Instability Index41.70

Aliphatic Index 66.96

Aromaticity 0.0884

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8634.67

LogP -99.48

H-bond Donors 314.0

H-bond Acceptors 284.0

Rotatable Bonds 670.0

Heavy Atoms 1429.0

Ring Count 32.0

Amide Bonds 196.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0135302 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence