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MYP_168960
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Basic Information
SV-473
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
22 amino acids
C121H192N32O34
Standard
Sequence
FLDSKAELEKARKILSEVGRWY
Physicochemical Analysis
2639.01 Da
8.43
0.77
0.55
0.0348
-0.56
0.79
-0.16
54.13
93.18
0.1364
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1101.96
-7.03
40.0
35.0
91.0
187.0
4.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031378 VERIFIED: YES
Provenance & Taxonomy
Murine respirovirus (Sendai virus) [Virus]
Virus-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor Fusion inhibitor Hemolytic
Sendai virus (Virus entry); Human RBCs
1 μM
Hemolysis
PaperA synthetic peptide corresponding to a conserved heptad repeat domain is a potent inhibitor of Sendai virus-cell fusion: an emerging similarity with functional domains of other viruses. | Rapaport D, Ovadia M, Shai Y. | EMBO J. 1995 | PMID:8521809 PMID8521809 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8521809/
RECORD: Rec_0301289 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/