Peptide Database

Peptide NameSyn-xiamencin-90

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC140H233N41O33

DescriptionStandard

        AKAQRLTLYLKEELRKRGKKAFIAW
    

Molecular Weight3018.60 Da

Isoelectric Point (pI)10.64

Net Charge (pH 7.0)5.80

Net Charge (pH 7.4) 5.59

Charge Density (pH 7.0) 0.2318

GRAVY Index-0.68

Hydrophobic Moment 0.55

Boman Index-0.27

Instability Index33.20

Aliphatic Index 94.00

Aromaticity 0.1200

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1251.46

LogP -7.30

H-bond Donors 46.0

H-bond Acceptors 39.0

Rotatable Bonds 107.0

Heavy Atoms 214.0

Ring Count 4.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036257 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50

RECORD: Rec_0153598 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity8.92 μM

MethodIC50