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MYP_168902
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C69H112N22O14
Standard
Sequence
RRGWALRLVLAY
Physicochemical Analysis
1473.77 Da
11.71
2.76
2.55
0.2299
0.26
0.16
-0.04
63.63
138.33
0.1667
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
605.14
-2.34
24.0
17.0
46.0
105.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0162373 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
sheep RBCs
15 μM
Hemolysis
PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
RECORD: Rec_0188760 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli
PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
RECORD: Rec_0237263 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
RECORD: Rec_0238877 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa
PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
RECORD: Rec_0268375 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
15 μM
Hemolysis
PaperRathinakumar R, Walkenhorst WF, Wimley WC. Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity. J Am Chem Soc. 2009 Jun 10;131(22):7609-7617. doi:10.1021/ja8093247. PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
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