Peptide Database

Peptide NameVIRIP[F12,L13,G15]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC114H167N21O26S

DescriptionStandard

        LEAIPMSIPPEFLFGKPFVF
    

Molecular Weight2279.74 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0618

GRAVY Index0.86

Hydrophobic Moment 0.21

Boman Index0.49

Instability Index44.76

Aliphatic Index 97.50

Aromaticity 0.2000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 701.91

LogP 0.70

H-bond Donors 21.0

H-bond Acceptors 26.0

Rotatable Bonds 66.0

Heavy Atoms 162.0

Ring Count 8.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359004 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyVIRIP

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor

TargetP4-CCR5

Activity1.34±0.42 μM

MethodIC50

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