Peptide Database

Peptide NameAtypical cationic antimicrobial peptide (Dermaseptin-S9), (DRS-S9)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC375H595N97O110S5

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICDEEKRENEDEENQEDDEQSEMRRGLRSKIWLWVLLMIWQESNKFKKM
    

Molecular Weight8382.64 Da

Isoelectric Point (pI)4.93

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -3.74

Charge Density (pH 7.0) -0.0505

GRAVY Index-0.47

Hydrophobic Moment 0.61

Boman Index-0.10

Instability Index76.07

Aliphatic Index 93.19

Aromaticity 0.1014

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3421.35

LogP -23.77

H-bond Donors 119.0

H-bond Acceptors 112.0

Rotatable Bonds 298.0

Heavy Atoms 587.0

Ring Count 10.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074472 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function