MYP_168847
Basic Information
Unnamed
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Antiparasitic Anti-Leishmania Antileishmanial
Antiparasitic General antiparasitic Antiparasitic
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
Standard
20 amino acids
C91H164N22O22
Standard
Sequence
LIGPVLGLVGSALGGLLKKI
Physicochemical Analysis
1918.41 Da
10.00
1.76
1.55
0.0879
1.49
0.49
0.56
12.56
190.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
679.70
-2.78
23.0
24.0
65.0
135.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0283443 VERIFIED: YES
Provenance & Taxonomy
Bombina variegata [Plant]
Bombinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic Antifungal
RECORD: Rec_0285126 VERIFIED: YES
Provenance & Taxonomy
Bombina variegata [Plant]
Bombinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic Antifungal
human red blood cell
RECORD: Rec_0326032 VERIFIED: YES
Provenance & Taxonomy
Bombina variegata [Plant]
Bombinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic Antifungal
Escherichia coli D21
4.8 μM
MIC
RECORD: Rec_0344365 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0358314 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Bombinin H4
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
D-allo-Ile at position 2
Bio-Activity Profile
Antimicrobial Antiparasitic Antileishmanial
Leishmania donovani MHOM/SD/00/IS-2D
1.7 μM
ED50; MTT assay
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