Peptide Database

Peptide NameNicomicin-1

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC161H249N43O43S2

DescriptionStandard

        GFWSSVWDGAKNVGTAIIKNAKVCVYAVCVSHK
    

Molecular Weight3539.09 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)2.82

Net Charge (pH 7.4) 2.53

Charge Density (pH 7.0) 0.0856

GRAVY Index0.38

Hydrophobic Moment 0.53

Boman Index0.22

Instability Index10.17

Aliphatic Index 88.48

Aromaticity 0.1212

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1383.49

LogP -12.52

H-bond Donors 51.0

H-bond Acceptors 49.0

Rotatable Bonds 113.0

Heavy Atoms 249.0

Ring Count 7.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414692 VERIFIED: YES

Provenance & Taxonomy

OrganismAnimalia [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

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