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MYP_168837
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Basic Information
Nicomicin-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
33 amino acids
C161H249N43O43S2
Standard
Sequence
GFWSSVWDGAKNVGTAIIKNAKVCVYAVCVSHK
Physicochemical Analysis
3539.09 Da
9.24
2.82
2.53
0.0856
0.38
0.53
0.22
10.17
88.48
0.1212
12490.00
12615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1383.49
-12.52
51.0
49.0
113.0
249.0
7.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0343637 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 209P
2 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0393491 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Rhodococcus sp.
0.125 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0405264 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0406594 VERIFIED: NO
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
2 μM
MIC
RECORD: Rec_0414692 VERIFIED: NO
Provenance & Taxonomy
Animalia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
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