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MYP_168837
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Basic Information
Nicomicin-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
33 amino acids
C161H249N43O43S2
Standard
Sequence
GFWSSVWDGAKNVGTAIIKNAKVCVYAVCVSHK
Physicochemical Analysis
3539.09 Da
9.24
2.82
2.53
0.0856
0.38
0.53
0.22
10.17
88.48
0.1212
12490.00
12615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1383.49
-12.52
51.0
49.0
113.0
249.0
7.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0339368 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ML-35p
16 μM
MIC
PaperNovel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain.
RECORD: Rec_0343637 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 209P
2 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0393491 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Rhodococcus sp.
0.125 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0405264 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0406594 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
2 μM
MIC
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