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MYP_168837
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Basic Information
Nicomicin-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
33 amino acids
C161H249N43O43S2
Standard
Sequence
GFWSSVWDGAKNVGTAIIKNAKVCVYAVCVSHK
Physicochemical Analysis
3539.09 Da
9.24
2.82
2.53
0.0856
0.38
0.53
0.22
10.17
88.48
0.1212
12490.00
12615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1383.49
-12.52
51.0
49.0
113.0
249.0
7.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0190635 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii
32 μM
MIC
PaperNovel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain.
RECORD: Rec_0208050 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
B. licheniformis
0.125 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0264163 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0297118 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
0.062 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0305079 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
32 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
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