Peptide Database

Peptide NameProgonadoliberin-2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC309H484N94O90S4

DescriptionStandard

        QHWSHGWYPGGKRELDSFEVSEEMKLCETGECSYMRPQRRSFLRNIVLDALARELQKRK
    

Molecular Weight7083.98 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)1.93

Net Charge (pH 7.4) 1.58

Charge Density (pH 7.0) 0.0327

GRAVY Index-1.00

Hydrophobic Moment 0.71

Boman Index-0.27

Instability Index85.56

Aliphatic Index 59.49

Aromaticity 0.1017

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3029.76

LogP -28.77

H-bond Donors 110.0

H-bond Acceptors 98.0

Rotatable Bonds 241.0

Heavy Atoms 497.0

Ring Count 12.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0252117 VERIFIED: YES

Provenance & Taxonomy

OrganismOryzias latipes [Animal]

FamilyProgonadoliberin

Tax ID8090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour