Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC508H850N136O127S8

DescriptionStandard

        MKLILIIAILLFQKSKVTEQLKRCWGEYIRGYCRKICRISEIREVLCENGRYCCLNSLKKKKKKKAPKSALPQPYPSQKIMYVGLKFVTLLDIQL
    

Molecular Weight11151.54 Da

Isoelectric Point (pI)9.88

Net Charge (pH 7.0)14.44

Net Charge (pH 7.4) 14.09

Charge Density (pH 7.0) 0.1520

GRAVY Index-0.11

Hydrophobic Moment 0.88

Boman Index-0.06

Instability Index30.98

Aliphatic Index 109.79

Aromaticity 0.0842

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4309.24

LogP -27.59

H-bond Donors 157.0

H-bond Acceptors 150.0

Rotatable Bonds 390.0

Heavy Atoms 779.0

Ring Count 13.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013608 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0306833 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal