Peptide Database

Peptide NameLachesicidin (Cathelicidin-related antimicrobial peptide) (CRAMP) (Vipericidin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length194 amino acids

Chemical FormulaC995H1541N249O306S7

DescriptionStandard

        MQGFFWKTWLVLAVCGTPASLAHRPLSYGEALELAVSVYNGKAGEASLYRLLEAVPQPEWDPSSEGSQQLNFTLKETACQVEEERSLEECGFQEDGVVLECTGYYFFGETPPVVVLSCVPVGGVEEEEEEEEEEQKAEAENDEEVEKEKEDEEKDQPKRVKRFKKFFKKVKKSVKKRLKKIFKKPMVIGVTFPF
    

Molecular Weight22111.82 Da

Isoelectric Point (pI)4.81

Net Charge (pH 7.0)-12.39

Net Charge (pH 7.4) -12.83

Charge Density (pH 7.0) -0.0639

GRAVY Index-0.58

Hydrophobic Moment 0.89

Boman Index-0.07

Instability Index59.35

Aliphatic Index 69.74

Aromaticity 0.1031

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24200.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8950.55

LogP -99.14

H-bond Donors 304.0

H-bond Acceptors 302.0

Rotatable Bonds 704.0

Heavy Atoms 1557.0

Ring Count 35.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211534 VERIFIED: YES

Provenance & Taxonomy

OrganismLachesis muta rhombeata [other]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetGram-negative and Gram-positive bacteria