Peptide Database

Peptide NameIFN-α14

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC869H1367N239O258S13

DescriptionStandard

        CNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFEFPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLEACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
    

Molecular Weight19707.44 Da

Isoelectric Point (pI)6.38

Net Charge (pH 7.0)-0.98

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0059

GRAVY Index-0.48

Hydrophobic Moment 0.64

Boman Index-0.10

Instability Index59.23

Aliphatic Index 76.39

Aromaticity 0.1024

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8162.71

LogP -81.13

H-bond Donors 284.0

H-bond Acceptors 273.0

Rotatable Bonds 676.0

Heavy Atoms 1379.0

Ring Count 26.0

Amide Bonds 187.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411463 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsN-linked glycosylation of asparagine residue at position 63; predicted disulphide bonds between cysteine residues at positions 1 and 99, and 29 and 39

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetInterferon-α/β receptor (Human)