‹ ›
MYP_168685
← PREVIOUS NEXT → BACK
Basic Information
CXCL11
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Binding / Molecular interaction ▸ Binding activity
Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide
Immunology ▸ Immune modulation ▸ Cytokine modulation
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Standard
73 amino acids
C368H623N107O98S6
Standard
Sequence
FPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF
Physicochemical Analysis
8306.93 Da
9.98
10.72
10.43
0.1469
-0.35
0.72
-0.13
33.78
89.45
0.0548
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3371.68
-29.79
119.0
115.0
292.0
579.0
8.0
79.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0044136 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0138302 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Listeria monocytogenes
8.0 μg/mL
MIC
PaperCutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity.
RECORD: Rec_0201721 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC29213
PMID12949249 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12949249/
RECORD: Rec_0220079 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
intercrine alpha (chemokine CxC) family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
9-36; 11-53
6-Arg: Citrulline; by PAD2
Bio-Activity Profile
Cytokine Growth factor intercrine alpha (chemokine CxC) family Chemokine-like Heparin-binding
PaperPDB 1RJT structural record; NMR; chain A; residues 1-73
RECORD: Rec_0284323 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC25922
PMID12949249 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12949249/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2