Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length236 amino acids

Chemical FormulaC1205H1856N278O352S8

DescriptionStandard

        IDDLAEVDYSLNSLPAVFRPFIDLDLKGIVYPAGNYTGPPYVAAPFTIPDQSDSMLHLAFSEYFFQTSSFAYYTAGAFSITIAEDVKSGKLICFLIIFFLQTCSYFNISTEIFGSIIPEVAKYSVTRYPVMLKLMATEIPIISLEQDSFTVEIRGSMEVIAVLPDSTTQSLFTMNIAANTSIALNIFDQKLVGSLCLNRLQFSLARSNVGFFEISLLENILSYILQTEVIPSANGK
    

Molecular Weight26125.80 Da

Isoelectric Point (pI)4.39

Net Charge (pH 7.0)-11.15

Net Charge (pH 7.4) -11.51

Charge Density (pH 7.0) -0.0473

GRAVY Index0.44

Hydrophobic Moment 0.60

Boman Index0.26

Instability Index43.16

Aliphatic Index 107.46

Aromaticity 0.1271

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0121323 VERIFIED: NO

Provenance & Taxonomy

OrganismPandion haliaetus (Osprey) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria