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MYP_168669
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Basic Information
KIK (Derived from PMAP-36)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C87H137N21O13
Standard
Sequence
WKIKWKIKWKIK
Physicochemical Analysis
1685.15 Da
10.70
5.75
5.54
0.4795
-1.05
0.30
-0.20
-33.28
97.50
0.2500
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
586.91
2.82
22.0
19.0
59.0
121.0
6.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0220918 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli 1005
PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
RECORD: Rec_0230842 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli 20411
2 μM
MIC
PaperDesign of Trp-Rich Dodecapeptides with Broad-Spectrum Antimicrobial Potency and Membrane-Disruptive Mechanism PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
RECORD: Rec_0243060 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhi C77-31
PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
RECORD: Rec_0276782 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 25923
PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
RECORD: Rec_0289151 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis 12250
PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
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