Peptide Database

Peptide NameNovel protein; similar to defensin; alpha 4; corticostatin (DEFA4)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC320H488N82O95S8

DescriptionStandard

        MPAQKQPPADDQDVVLYFSGDDSCSLQVPGSTKGLICHCRVLYCIFGEHLGGTCFILGERYPICCY
    

Molecular Weight7260.31 Da

Isoelectric Point (pI)4.91

Net Charge (pH 7.0)-3.39

Net Charge (pH 7.4) -3.82

Charge Density (pH 7.0) -0.0514

GRAVY Index0.10

Hydrophobic Moment 0.43

Boman Index0.15

Instability Index52.42

Aliphatic Index 79.70

Aromaticity 0.1061

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2779.83

LogP -25.62

H-bond Donors 100.0

H-bond Acceptors 102.0

Rotatable Bonds 228.0

Heavy Atoms 505.0

Ring Count 14.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0302844 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Non-hemolytic Non-ribosomal