Peptide Database

Peptide NameChicken LEAP-2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC190H318N64O57S5

DescriptionStandard

        MTPFWRGVSLRPIGASCRDDSECVTRLCRKRRCSLSVAQE
    

Molecular Weight4571.28 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)3.47

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0868

GRAVY Index-0.41

Hydrophobic Moment 0.62

Boman Index-0.26

Instability Index71.27

Aliphatic Index 65.75

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1989.65

LogP -24.15

H-bond Donors 78.0

H-bond Acceptors 66.0

Rotatable Bonds 151.0

Heavy Atoms 316.0

Ring Count 5.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100675 VERIFIED: YES

Provenance & Taxonomy

OrganismPteropus vampyrus [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)