Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC224H358N60O75S5

DescriptionStandard

        MKNSKDILNNAIEEVSEKELMEVAGGKRGTGWFATITDDCPNSVFVCC
    

Molecular Weight5251.92 Da

Isoelectric Point (pI)4.55

Net Charge (pH 7.0)-3.52

Net Charge (pH 7.4) -3.79

Charge Density (pH 7.0) -0.0732

GRAVY Index-0.22

Hydrophobic Moment 0.57

Boman Index0.02

Instability Index42.63

Aliphatic Index 71.04

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2196.14

LogP -24.22

H-bond Donors 77.0

H-bond Acceptors 77.0

Rotatable Bonds 178.0

Heavy Atoms 364.0

Ring Count 5.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204476 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus salivarius [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence