Peptide Database

Peptide NameBeta-defensin 37 (BD-37) (mBD-37) (Defensin; beta 37)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC308H496N86O87S8

DescriptionStandard

        MKFSYFLLLLLSLSNFQNNPVAMLDTIACIENKDTCRLKNCPRLHNVVGTCYEGKGKCCHKN
    

Molecular Weight7052.28 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0583

GRAVY Index-0.09

Hydrophobic Moment 0.55

Boman Index0.01

Instability Index28.09

Aliphatic Index 86.45

Aromaticity 0.0806

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2813.88

LogP -27.47

H-bond Donors 101.0

H-bond Acceptors 101.0

Rotatable Bonds 237.0

Heavy Atoms 489.0

Ring Count 9.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0369362 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic