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MYP_168612
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Basic Information
Kalata B7-Y15S
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C122H200N36O41S6
Standard
Sequence
GLPVCGETCTLGTCSTQGCTCSWPICKRN
Physicochemical Analysis
3019.50 Da
7.78
0.70
0.41
0.0242
0.06
0.31
0.08
52.79
50.34
0.0345
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1229.34
-18.11
49.0
48.0
93.0
205.0
4.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0158882 VERIFIED: YES
Provenance & Taxonomy
Oldenlandia affinis [Plant]
Cyclotide
Structure & Mods
backbone-cyclized cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
160 μM
MIC
PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0229612 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cyclotide
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 28669767 PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0256497 VERIFIED: YES
Provenance & Taxonomy
Oldenlandia affinis [Plant]
Cyclotide
Structure & Mods
backbone-cyclized cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
160 μM
MIC
PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0298046 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cyclotide
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
U-937/GTB
IC50
PaperPubMed PMID: 28669767 PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0304847 VERIFIED: YES
Provenance & Taxonomy
Oldenlandia affinis [Plant]
Cyclotide
Structure & Mods
backbone-cyclized cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans
60 μM
MIC
PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
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