Peptide Database

Peptide NameBovine neutrophil beta-defensin 12

Function Ontology

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Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC147H256N50O38S5

DescriptionStandard

        AVGRKASVVLTRCPRTMRQIGTCFGPPVKCCR
    

Molecular Weight3492.24 Da

Isoelectric Point (pI)10.83

Net Charge (pH 7.0)6.75

Net Charge (pH 7.4) 6.50

Charge Density (pH 7.0) 0.2111

GRAVY Index0.02

Hydrophobic Moment 0.78

Boman Index-0.13

Instability Index22.84

Aliphatic Index 66.88

Aromaticity 0.0312

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1424.60

LogP -16.71

H-bond Donors 56.0

H-bond Acceptors 50.0

Rotatable Bonds 112.0

Heavy Atoms 240.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164192 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis canadensis [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)