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MYP_168562
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Basic Information
Protegrin-1 (PG-1)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C82H138N32O19S4
Standard
Sequence
RGGRLCYCRRFCVCVGR
Physicochemical Analysis
2004.44 Da
9.88
4.72
4.46
0.2776
0.00
0.63
-0.32
31.51
57.06
0.1176
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
858.65
-9.37
38.0
28.0
65.0
137.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0074330 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 29213 >128
2 μM
MIC
PMID31416220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31416220/
RECORD: Rec_0140632 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
P. auruginosa 27853
8 μM
MIC
PMID31416220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31416220/
RECORD: Rec_0145272 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis 12228
8 μM
MIC
PMID31416220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31416220/
RECORD: Rec_0155956 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli 25922
4 μM
MIC
PMID31416220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31416220/
RECORD: Rec_0266542 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli K88
2 μM
MIC
PMID31416220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31416220/
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