Peptide Database

Peptide NameOfatumumab

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length222 amino acids

Chemical FormulaC1053H1626N280O329S7

DescriptionStandard

        EVQLVESGGGLVQPGRSLRLSCAASGFTFNDYAMHWVRQAPGKGLEWVSTISWNSGSIGYADSVKGRFTISRDNAKKSLYLQMNSLRAEDTALYYCAKDIQYGNYYYGMDVWGQGTTVTVSSASTKGPSVFPLAPGSSKSTSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
    

Molecular Weight23696.31 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)4.06

Net Charge (pH 7.4) 3.63

Charge Density (pH 7.0) 0.0183

GRAVY Index-0.19

Hydrophobic Moment 0.56

Boman Index0.09

Instability Index41.52

Aliphatic Index 72.84

Aromaticity 0.1036

Extinction Coeff. Reduced 45380.00

Extinction Coeff. Oxidized 45630.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066770 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMonoclonal antibody

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory

Half-LifeApproximately 14 days. Range: 2.3 to 61.5 days