Peptide Database

Peptide NameCathelicidin-1/ CATH-1 / Fowlicidin-1 [P7K][T12L][I14K][G16L][N18K]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC157H274N46O29

DescriptionStandard

        RVKRVWKLVIRLVKALYKLYRAIKKK
    

Molecular Weight3270.15 Da

Isoelectric Point (pI)11.63

Net Charge (pH 7.0)10.75

Net Charge (pH 7.4) 10.53

Charge Density (pH 7.0) 0.4135

GRAVY Index-0.16

Hydrophobic Moment 0.93

Boman Index-0.26

Instability Index3.64

Aliphatic Index 142.31

Aromaticity 0.1154

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1276.81

LogP -2.96

H-bond Donors 49.0

H-bond Acceptors 40.0

Rotatable Bonds 117.0

Heavy Atoms 232.0

Ring Count 4.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012423 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity7.6 μM

MethodMIC

RECORD: Rec_0131569 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity1 μM

MethodHemolysis

RECORD: Rec_0236591 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetListeria monocytogenes ATCC 19115

Activity7.6 μM

MethodMIC

RECORD: Rec_0313818 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 25923

Activity1.9 μM

MethodMIC

RECORD: Rec_0422423 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetSalmonella enterica subsp. enterica serovar Typhimurium ATCC 14028

Activity1.9 μM

MethodMIC