Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC356H552N90O107S13

DescriptionStandard

        MKNSQQVAVLLAFVLLVSMSPPGFAAKCLPEETCTSFIYTGACEASNCYMDCVAAYKGVGEGQCFPQGCRCSYCCKP
    

Molecular Weight8221.57 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-0.59

Net Charge (pH 7.4) -0.98

Charge Density (pH 7.0) -0.0077

GRAVY Index0.31

Hydrophobic Moment 0.49

Boman Index0.18

Instability Index50.15

Aliphatic Index 63.38

Aromaticity 0.1039

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3104.98

LogP -33.12

H-bond Donors 114.0

H-bond Acceptors 120.0

Rotatable Bonds 260.0

Heavy Atoms 566.0

Ring Count 13.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0260931 VERIFIED: NO

Provenance & Taxonomy

OrganismLeersia perrieri [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence