Peptide Database

Peptide NameInterleukin-22

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC739H1186N206O219S9

DescriptionStandard

        APISSHCRLDKSNFQQPYITNRTFMLAKEASLADNNTDVRLIGEKLFHGVSMSERCYLMKQVLNFTLEEVLFPQSDRFQPYMQEVVPFLARLSNRLSTCHIEGDDLHIQRNVQKLKDTVKKLGESGEIKAIGELDLLFMSLRNACI
    

Molecular Weight16749.16 Da

Isoelectric Point (pI)7.10

Net Charge (pH 7.0)0.13

Net Charge (pH 7.4) -0.36

Charge Density (pH 7.0) 0.0009

GRAVY Index-0.26

Hydrophobic Moment 0.70

Boman Index-0.04

Instability Index47.80

Aliphatic Index 92.81

Aromaticity 0.0753

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6910.31

LogP -65.92

H-bond Donors 240.0

H-bond Acceptors 232.0

Rotatable Bonds 572.0

Heavy Atoms 1173.0

Ring Count 20.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166788 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-10 family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-99; 56-145

Bio-Activity Profile

Function

Cytokine Growth factor IL-10 family