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MYP_168469
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Basic Information
Brevinin-2GU
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
30 amino acids
C135H238N40O40S2
Standard
Sequence
GVIIDTLKGAAKTVAAELLRKAHCKLTNSC
Physicochemical Analysis
3125.71 Da
9.31
2.83
2.54
0.0942
0.30
0.55
0.07
2.78
114.00
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1300.49
-13.64
48.0
46.0
108.0
217.0
1.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0323069 VERIFIED: YES
Provenance & Taxonomy
Hylarana guntheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
24-30
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli
32 μM
MIC
PaperA Potent, Non-Toxic Insulin-Releasing Peptide Isolated From an Extract of the Skin of the Asian Frog, Hylarana Guntheri (Anura:Ranidae)
RECORD: Rec_0338424 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cytolytic
Human erythrocytes
700 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/18501981/ PMID18501981 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18501981/
RECORD: Rec_0348631 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0427339 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
P. acnes strain 29903
25 μM
MIC
PMID22374306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22374306/
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