Peptide Database

Peptide NameBeta-defensin 1 (BD-1) (Defensin; beta 1)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC320H506N86O93S8

DescriptionStandard

        MRTSYLLLFTLCLLLSEIASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYGGKAKCCK
    

Molecular Weight7302.48 Da

Isoelectric Point (pI)8.77

Net Charge (pH 7.0)3.60

Net Charge (pH 7.4) 3.17

Charge Density (pH 7.0) 0.0530

GRAVY Index0.26

Hydrophobic Moment 0.44

Boman Index0.16

Instability Index38.23

Aliphatic Index 83.24

Aromaticity 0.1029

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2860.11

LogP -31.39

H-bond Donors 109.0

H-bond Acceptors 107.0

Rotatable Bonds 240.0

Heavy Atoms 507.0

Ring Count 10.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0167971 VERIFIED: YES

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyBeta-defensin; Defensin

Tax ID9595

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic