Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC401H606N106O105S9

DescriptionStandard

        MALSREMFYFGFALFFIAVQWPSGSWAGLEYSQSFPGGEFAVCETCRLGRGKCRKVCLDSEKIAGKCKLNFFCCRERI
    

Molecular Weight8880.33 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)3.44

Net Charge (pH 7.4) 3.10

Charge Density (pH 7.0) 0.0441

GRAVY Index0.11

Hydrophobic Moment 0.63

Boman Index0.08

Instability Index28.78

Aliphatic Index 63.85

Aromaticity 0.1667

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3391.96

LogP -27.53

H-bond Donors 128.0

H-bond Acceptors 118.0

Rotatable Bonds 292.0

Heavy Atoms 621.0

Ring Count 17.0

Amide Bonds 80.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0281680 VERIFIED: NO

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10036

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic