Peptide Database

Peptide NamePreprofallaxidin-8 [Cleaved into: Fallaxidin-2.1; Fallaxidin-3.2; Fallaxidin-5.2]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC578H922N160O164S4

DescriptionStandard

        MASLKKSLFLVLFLGLLSLSICEEQKRENEEDAEDENHEEESEEKRGLLDFAKHVIGIASKLGKRSEEKRFWPFMGKRSEEKRFWPFMGKRSEEKRFFRVLAKLGKLAK
    

Molecular Weight12864.74 Da

Isoelectric Point (pI)9.04

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.32

Charge Density (pH 7.0) 0.0248

GRAVY Index-0.74

Hydrophobic Moment 0.91

Boman Index-0.20

Instability Index80.18

Aliphatic Index 74.31

Aromaticity 0.1009

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5319.52

LogP -41.95

H-bond Donors 188.0

H-bond Acceptors 173.0

Rotatable Bonds 460.0

Heavy Atoms 906.0

Ring Count 17.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005576 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetE. cloacae (Gram-negative)

RECORD: Rec_0024523 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetB. cereus (Gram-positive)

RECORD: Rec_0039597 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

RECORD: Rec_0078761 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. epidermidis (Gram-positive)

RECORD: Rec_0087473 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEnterococcus faecalis (Gram-positive)

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